John Wayne Casserole Recipe

John Wayne Casserole

A hearty, Tex-Mex–style casserole with a biscuit crust, seasoned beef, veggies, and a creamy cheese topping.


Ingredients

Crust Layer

  • 2 cups Bisquick (or similar baking mix)

  • ½ cup water (or as needed to form a soft dough)

Beef Layer

  • 1 lb ground beef

  • 1 packet taco seasoning

  • ⅓ cup water

Vegetable Layer

  • 1 small onion, chopped

  • 1 medium green bell pepper, chopped

  • 1 medium red bell pepper, chopped

  • 1–2 jalapeños, seeded & sliced (optional, for heat)

  • 2–3 tomatoes, chopped (or 1 can Rotel drained)

Creamy Cheese Layer

  • 1 cup sour cream

  • ½ cup mayonnaise

  • 2 cups shredded cheddar cheese (divided)

  • 1 teaspoon garlic powder

  • ½ teaspoon salt

  • ½ teaspoon pepper


Instructions

1. Prepare the crust

  1. Preheat oven to 350°F (175°C).

  2. In a bowl, mix Bisquick + water until a soft dough forms.

  3. Press the dough evenly into a 9×13-inch baking dish.

  4. Bake 10 minutes to set the crust slightly.


2. Cook the beef

  1. In a skillet, cook the ground beef over medium heat until browned.

  2. Drain excess grease.

  3. Add taco seasoning + ⅓ cup water.

  4. Simmer for 2–3 minutes until thickened.


3. Layer the vegetables

  1. Spread onions, bell peppers, jalapeños, and tomatoes (or Rotel) over the pre-baked crust.

  2. Spread the seasoned beef evenly over the vegetables.


4. Make the creamy topping

  1. In a bowl, mix:

    • Sour cream

    • Mayonnaise

    • 1 cup cheddar cheese

    • Garlic powder, salt & pepper

  2. Stir until smooth.

  3. Spread this mixture evenly over the beef layer.

  4. Top with the remaining 1 cup cheddar.


5. Bake

Bake at 350°F (175°C) for 25–30 minutes,
or until bubbly, golden, and cooked through.


Serve

Let cool for 5–10 minutes, then slice and serve.
Pairs well with:

  • Salad

  • Corn

  • Rice

  • Chips & salsa


Tips & Variations

Make it spicier

  • Add hot Rotel

  • Use pepper jack cheese

  • Extra jalapeños

Make it lighter

  • Use Greek yogurt instead of sour cream

  • Use 90–93% lean beef

Add-ins

  • Black olives

  • Black beans (drained)

  • Corn

  • Green chiles

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